Meclizine |
Meclizine (proposed INN is meclozine) is an antihistamine considered to be an antiemetic.
It is most commonly used to inhibit nausea and vomiting. An alternative
to dimenhydrinate (Dramamine), meclizine is considered to be equally effective,
but with reduced side effects. Uses Motion sickness Meclizine is effective in inhibiting the symptoms of motion sickness, such as nausea, vomiting, and dizziness. Vertigo Meclizine may be effective in relieving vertigo experienced as a result of inner ear infections or other conditions. Risks of use Drowsiness Drowsiness may result as a side effect of taking meclizine. While the effects are less than dimenhydrinate, users are advised not to operate heavy machinery while under the influence. The consumption of alcohol while under the influence of meclizine may result in additional drowsiness. Pregnancy Meclizine is classified as Pregnancy Category B by the FDA. Category B: Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women. This section does not cite any references or sources. Please improve this section by adding citations to reliable sources. Unverifiable material may be challenged and removed. (July 2007) Studies have shown that cleft palates of fetuses were formed when pregnant rats were exposed to 25-50 times a normal dosage. Thus, pregnant women are advised not to take meclizine unless it is absolutely necessary. Anticholinergics Due to its possible anticholinergic action, meclizine should be used carefully with patients who suffer from asthma, glaucoma, or an enlarged prostate gland. Commercial names Meclizine hydrochloride is sold under the commercial names Dramamine II® Dramamine Less Drowsy® Motion Sickness 2 (Longs drugstore brand) Antivert® Bonine® Bonamine® Bonikraft® Emetostop® Medivert® Sea-Legs® Agyrax® Postafen® (Sweden) |